Zpět
Ing. Jana Svobodová, Ph.D.
- Pracoviště: PřF - Katedra chemie
- odborný asistent
- E-mail: jana.svobodova.4@uhk.cz
- Telefon: 493332839
- Budova: S
- Místnost: 73320 3. podlaží
Publikace na UHK
PRCHALOVÁ, Eliška, M. SUKUPOVA, D. MALIŇÁK, R. ANDRÝS, L. SIVAK, V. PEKARIK, A. SKARKA, J. SVOBODOVÁ, L. PRCHAL, L. FRESSER, Z. HEGER, K. MUSÍLEK. BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles for enhanced bioavailability in the CNS. Biomedicine and Pharmacotherapy. 2023, 167 (November), "Article Number:115490". ISSN 0753-3322.
HANZLOVÁ, Michaela, M. SEDLÁČEK MIŠKEŘÍKOVÁ, A. ROTTEROVÁ, K. CHALUPOVÁ, K. JURKOVÁ, M. HAMŠÍKOVÁ, R. ANDRÝS, A. HALEČKOVÁ, J. SVOBODOVÁ, M. SCHMIDT, O. BENEK, K. MUSÍLEK. Nanomolar Benzothiazole-Based Inhibitors of 17β-HSD10 with Cellular Bioactivity. ACS Medicinal Chemistry Letters. 2023, 14 (12), 1724-1732. ISSN 1948-5875.
MIKYSKOVA, Romana, O. SAPEGA, M. PSOTKA, O. NOVOTNY, Z. HODNY, S. BALINTOVA, D. MALIŇÁK, J. SVOBODOVÁ, R. ANDRÝS, D. RYSANEK, K. MUSÍLEK, M. REINIS. STAT3 inhibitor Stattic and its analogues inhibit STAT3 phosphorylation and modulate cytokine secretion in senescent tumour cells. Molecular Medicine Reports. 2023, 27 (4), "Article Number: 81". ISSN 1791-2997.
ZORBAZ, Tamara, D. MALIŇÁK, T. HOFMANOVÁ, N. MARAKOVIC, S. ZUNEC, NM. HRVAT, R. ANDRÝS, M. PSOTKA, A. ZANDONA, J. SVOBODOVÁ, L. PRCHAL, S. FINGLER, M. KATALINIC, Z. KOVARIK, K. MUSÍLEK. Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents. European Journal of Medicinal Chemistry. 2022, 238 (August), "Article Number: 114377". ISSN 0223-5234.
KOHOUTOVÁ, Zuzana, D. MALIŇÁK, R. ANDRÝS, J. SVOBODOVÁ, M. PSOTKA, M. SCHMIDT, L. PRCHAL, K. MUSÍLEK. Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides. Journal of enzyme inhibition and medicinal chemistry. 2022, 37 (1), 760-767. ISSN 1475-6366.
OLEKŠÁK, Patrik, M. PSOTKA, M. VANCUROVA, O. SAPEGA, J. BIEBLOVA, M. REINIS, D. RYSANEK, R. MIKYSKOVA, K. CHALUPOVÁ, D. MALIŇÁK, J. SVOBODOVÁ, R. ANDRÝS, H. ŘEHULKOVÁ, V. ŠKOPEK, NL. PHAM, J. BARTEK, Z. HODNY, K. MUSÍLEK. Design, synthesis, and in vitro evaluation of BP-1-102 analogs with modified hydrophobic fragments for STAT3 inhibition. Journal of enzyme inhibition and medicinal chemistry. 2021, 36 (1), 410-424. ISSN 1475-6366.
