Grant Agency of the Czech Republic

The Grant Agency of the Czech Republic (GACR) was established by Act No. 300/1992 Coll., on state support of research and development, in 1992 as an independent institution supporting basic scientific research in the Czech Republic.

The task of the GACR is to annually award grants to the best basic research projects in all fields of science based on a public tender in research and development. Another task of the Agency is also to check the progress of solution and fulfilment of project objectives for each past year and to evaluate the achieved results of the projects after their completion.

Website of the Grant Agency of the Czech Republic

Projects at the Faculty of Science, University of Hradec Králové:

 

24-10031K Graded differential geometry with applications

Researcher for the Czech Republic: Oleksii Kotov, Dr., Department of Mathematics
Co-researcher: Ing. Jan Vysoký, Ph.D., Czech Technical University in Prague - Faculty of Nuclear Sciences and Physical Engineering
Researcher for Poland: Janusz Grabowski, Polish Academy of Science - Institute of Mathematics
Realization period: 01/2024 – 12/2026

24-12234S Evaluation of chiral SFC-MS for the analysis of positional isomers and enantiomers of biologically significant lipids

Researcher: assoc. prof. Miroslav Lísa, Ph.D. , Department of Chemistry
Realization period: 01/2024 – 12/2026

23-05857S Alzheimer´s disease and aging: can mTOR inhibitors kill two birds with one drug?

Researcher: Mgr. Eugenie Nepovimová Ph.D. , Department of Chemistry
Co-researcher 1: MUDr. Zdeněk Hodný, CSc., Institute of Molecular Geneticsof the Czech Academy of Sciences
Co-researcher 2: RNDr. Karel Valeš, Ph.D., National Institute of Mental Health
Realization period: 01/2023 – 12/2025

23-42701L Research of multifunctional compounds targeting neuroinflammation and cholinergic deficit in Alzheimer’s disease

Researcher for the Czech Republic: prof. PharmDr. Kamil Musílek, Ph.D., Department of Chemistry
Researcher for Poland: Kinga Salat, Jagiellonian University Medical College, Faculty of Pharmacy
Researcher for Slovenia: Stanislav Gobec, University of Ljubljana, Faculty of Pharmacy 
Realization period: 01/2023 – 12/2025

22-14568S Biodistribution and real-time monitoring of free or apoferritin-encapsulated charged cholinesterase reactivators

Researcher: prof. PharmDr. Kamil Musílek, Ph.D., Department of Chemistry
Co-researcher 1: Mgr. Zbyněk Heger, Ph.D., Mendel University in Brno, Faculty of AgriSciences
Co-researcher 2: Ing. Zenon Starčuk CSc., The Czech Academy of Sciences, Institute of Scientific Instruments
Realization period: 01/2022 – 12/2024

22-13967S Development of methods for comprehensive monitoring of metabolite changes in central nervous system disorders

Researcher: doc. Ing. Miroslav Lísa, Ph.D., Department of Chemistry
Realization period: 01/2022 – 12/2024

22-18739S Asymptotic and spectral analysis of operators in mathematical physics

Researcher: RNDr. Jiří Lipovský, Ph.D., Department of Physics
Realization period: 01/2022 – 12/2024

21-03000S Modified nucleophiles for reactivation of cholinesterases inhibited by organophosphorus compounds

Researcher on behalf of FS UHK: RNDr. Dávid Maliňák, Ph.D., Department of Chemistry
Researcher: prof. PharmDr. Kamil Musílek, Ph.D., University Hospital of Hradec Králové
Realization period: 01/2021 – 12/2023

20-22037S The therapeutic potential of novel mTOR inhibitors within the process of ageing

Researcher: Mgr. Eugenie Nepovimová, Ph.D., Department of Chemistry
Realization period: 01/2020 – 12/2022

20-12289S The coupling of supercritical fluid chromatography with mass spectrometry as a new tool for characterization of lipids and polar metabolites

Researcher: doc. Ing. Miroslav Lísa, Ph.D., Department of Chemistry
Realization period: 01/2020 – 12/2022

20-19018Y Delicate analytical and topological tools for variational problems and modelling

Researcher: Mgr. Daniel Campbell, Ph.D., Department of Mathematics
Realization period: 01/2020 – 12/2022

19-01866S Old Landslides: Really Inactive?

Researcher: doc. RNDr. Karel Šilhán, Ph.D., Department of Biology 
Realization period: 01/2019 – 12/2021

19-13628S Encapsulation of Cholinesterase Reactivators with Apoferitin to Increase Bioavailability in the Central Nervous System

Researcher: prof. PharmDr. Kamil Musílek, Ph.D., Department of Chemistry
Realization period: 01/2019 – 12/2021

19-14466Y Special Metrics in Super Gravity and New G-Structures

Researcher: Dr. Ioannis Chrysikos, Ph.D., Department of Mathematics
Realization period: 03/2019 - 12/2021

19-11867S Research on the Mechanism of Toxicity of S-conjugates of Aminophenolic Drugs

Researcher at  FS UHK: prof. PharmDr. Kamil Musílek, Ph.D., Department of Chemistry
Researcher: doc. RNDr. Tomáš Roušar, Ph.D, University of Pardubice, Faculty of Chemical Technology
Realization period: 01/2019 – 12/2021

18-19722Y Trade-Off between Radial Trunk Growth and Fruit Yield in relation to the Xylem Properties in Grafted Apple and Pear Trees

Researcher: RNDr. Lenka Plavcová, Ph.D., Department of Biology
Realization period: 01/2018 – 12/2020

18-00496S Singular Spaces from Special Holonomy and Foliation

Researcher: doc. Anton Galaev, DSc., Department of Mathematics
Realization period: 01/2018 – 12/2020

18-01734S Butyrylcholinesterase Reactivators for the Preparation of Pseudo-Catalytic Scavengers Useful in Intoxications with Organophosphorus Compounds

Researcher on behalf of FS UHK: prof. Ing. Kamil Kuča, Ph.D., Department of Chemistry
Researcher: prof. PharmDr. Kamil Musílek, Ph.D., University Hospital of Hradec Králové 
Realization period: 01/2018 – 12/2020

18-14259S Inhibition of the JAK/STAT3 Signaling Pathway in the Treatment of Tumors

Researcher on behalf of FS UHK: doc. PharmDr. Kamil Musílek, Ph.D., Department of Chemistry
Researcher: MUDr. Zdeněk Hodný, CSc., Ústav molekulární genetiky AV ČR, v.v.i. 
Realization period: 01/2018 – 12/2020

18-08937S Research of Oxime-CB(7) Complexes in the Transmission of Quaternary Acetylcholinesterase Reactivators into the Central Nervous System

Researcher on behalf of FS UHK: Ing. Miroslav Lísa, Ph.D. Department of Chemistry
Researcher: doc. PharmDr. Jana Žďárová Karasová, Ph.D., University of Defence, Faculty of Military Health Sciences Hradec Králové
Realization period: 01/2018 – 12/2020

17-19968S Localized Electronic Effects of Antibody Binding on NanoComposite Materials (LEEFAB)

Researcher on behalf of FS UHK: prof. Ing. Kamil Kuča, Ph.D., Department of Chemistry
Researcher: doc. RNDr. Bohuslav Rezek Ph.D,  Czech Technical University in Prague, Faculty of Electrical Engineering
Realization period: 01/2017 – 12/2019

15-14180Y Spectral and resonance properties of quantum models
Researcher: RNDr. Jiří Lipovský, Ph.D., Department of Physics

Researcher: RNDr. Jiří Lipovský, Ph.D., Department of Physics
Realization period: 01/2015 – 12/2027